DrugRepV_3375 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3376 | Mycophenolic Acid-Betaferon | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | NA | 24096239 |
DrugRepV_3377 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3378 | Intron A | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3379 | Avonex | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3380 | Rebif | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3381 | Betaferon | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3382 | Betaferon | NA | Multiple sclerosis | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3383 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (90 %) | Approved | 24096239 |
DrugRepV_3384 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (90 %) | Approved | 24096239 |
DrugRepV_3385 | Intron A | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (90 %) | Approved | 24096239 |
DrugRepV_3386 | Avonex | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (90 %) | Approved | 24096239 |
DrugRepV_3387 | Rebif | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (90 %) | Approved | 24096239 |
DrugRepV_3388 | Betaferon | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (90 %) | Approved | 24096239 |
DrugRepV_3389 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (99 %) | Approved | 24096239 |
DrugRepV_3390 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (99 %) | Approved | 24096239 |
DrugRepV_3391 | Intron A | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (99 %) | Approved | 24096239 |
DrugRepV_3392 | Avonex | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (99 %) | Approved | 24096239 |
DrugRepV_3393 | Rebif | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (99 %) | Approved | 24096239 |
DrugRepV_3394 | Betaferon | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (99 %) | Approved | 24096239 |
DrugRepV_4125 | 3-{3-[(1E)-1-(hydroxyimino)ethyl]phenyl}-5-methyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4126 | 3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-5-methyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4127 | 5-ethyl-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4128 | 3-(3-acetylphenyl)-5-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4129 | 5-(aminomethyl)-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4130 | 3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-5-sulfanyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4131 | 3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-5-(methylsulfanyl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4132 | 3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-5-(methylamino)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4133 | 5-ethyl-3-{3-[(1E)-1-{[2-(4-methylpiperazin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4134 | 5-ethyl-3-{3-[(1E)-1-{[2-(morpholin-4-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4135 | 5-ethyl-3-{3-[(1E)-1-{[2-(thiomorpholin-4-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4136 | 3-{3-[(1E)-1-{[2-(diethylamino)ethoxy]imino}ethyl]phenyl}-5-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4137 | 3-{3-[(1E)-1-{[2-(cyclohexylamino)ethoxy]imino}ethyl]phenyl}-5-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4138 | 5-ethyl-3-{3-[(1E)-1-{[2-(piperidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4139 | 5-ethyl-3-{3-[(1E)-1-{[2-(pyrrolidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4140 | 3-{3-[(1E)-1-({2-[4-(dimethylamino)piperidin-1-yl]ethoxy}imino)ethyl]phenyl}-5-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4522 | IFN-alpha2a | Antineoplastic and Immunomodulating Agents | Hepatitis C virus | Hairy cell leukemia | AIDS-related Kaposi's sarcoma | Leukemia | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved, Investigational | 15200845 |
DrugRepV_4523 | IFN-alpha2b | Antineoplastic and Immunomodulating Agents | Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4524 | IFN-alphan1 | Antineoplastic and Immunomodulating Agents | Venereal or genital warts caused by the Human Papiloma Virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (100 %) | Approved, Investigational | 15200845 |
DrugRepV_4525 | IFN-alphan3 | NA | Condylomata acuminata | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (100 %) | Approved, Investigational | 15200845 |
DrugRepV_4526 | IFN-beta1a | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Condyloma acuminatum | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved, Investigational | 15200845 |
DrugRepV_4527 | IFN-beta1b | Antineoplastic and Immunomodulating Agents | Multiple sclerosis | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (100 %) | Approved | 15200845 |
DrugRepV_4528 | Acyclovir | Dermatologicals; Antiinfectives For Systemic Use; Sensory Organ | Viral infections (Herpes simplex, Zoster and varicella zoster) | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4529 | Ganciclovir | Antiinfectives For Systemic Use | Cytomegalovirus infection | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved, Investigational | 15200845 |
DrugRepV_4530 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (100 %) | Approved | 15200845 |
DrugRepV_4531 | Indinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4532 | Nelfinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4533 | Saquinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved, Investigational | 15200845 |
DrugRepV_4534 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4535 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4536 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4537 | Zanamivir | Antiinfectives For Systemic Use | Influenza virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4538 | Amantadine | Nervous System | Influenza and Parkinson Disease | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4539 | Foscarnet | Antiinfectives For Systemic Use | Cytomegalovirus retinitis | Herpesviruses | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_5069 | Alisporivir | NA | Hepatitis C virus | Middle East respiratory syndrome coronavirus | N3/Jordan | NA | CPE inhibition assay | Decrease (50 %) | Investigational | 27840112 |
DrugRepV_5070 | Alisporivir | NA | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | MA-15 | NA | CPE inhibition assay | Decrease (50 %) | Investigational | 27840112 |
DrugRepV_6232 | YK 51 | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (92 %) | NA | 20567498 |
DrugRepV_6233 | YK 73 | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (90 %) | NA | 20567498 |
DrugRepV_6234 | YK 73x | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (91 %) | NA | 20567498 |
DrugRepV_6235 | YK 101 | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (94 %) | NA | 20567498 |
DrugRepV_6236 | YK 38 | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (83 %) | NA | 20567498 |
DrugRepV_7405 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]uracil | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7406 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]thymine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7407 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorouracil | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7408 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]cytosine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7409 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorocytosine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7410 | L-Neplanocin A | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7411 | (1S,2R,3S)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl] hypoxanthine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7412 | (1S,2R,3S)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]guanine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7413 | Cyclopentenyl nucleosides | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7414 | (1R,2S,3R)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl] hypoxanthine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7415 | (1R,2S,3R)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]guanine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7416 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]uracil | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7417 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]thymine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7418 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorouracil | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7419 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]cytosine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7420 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorocytosine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |